Description
This product is a recombinant human IgG1, lambda antibody that is designed to target human CSF2 with specificity. It cross-reacts with rhesus, mouse, and marmoset CSF2. The affinity levels towards recombinant hGM-CSF sourced from yeast and E. coli by this antibody are quantified at 0.36 nM and 0.15 nM, respectively. Furthermore, it possesses the capability to inhibit GM-CSF-dependent proliferation of DCs.
Target
CSF2
Target Alias Names
Colony Stimulating Factor 2, Sargramostim, Molgramostin, Colony Stimulating Factor 2 (Granulocyte-Macrophage), GMCSF, CSF
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression