Description
This product is a recombinant human antibody,which binds to and neutralizes human CD47. The CD47 protein may play a role in membrane trafficking and signal transduction. Disorders associated with CD47 include hereditary spherocytosis and thrombocytthenia 1.
Target
CD47
Target Alias Names
CD47 Molecule, Antigenic Surface Determinant Protein OA3, CD47 Antigen (Rh-Related Antigen, Integrin-Associated Signal Transducer), Antigen Identified By Monoclonal Antibody 1D8, Leukocyte Surface Antigen CD47, Integrin Associated Protein, Rh-Related Antigen, CD47 Glycoprotein
Isotypes/Mimetics
Chimeric (mouse/human) IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression