Description
This is a chimeric monoclonal antibody derived from murine antibody B4, which specifically binds to an extracellular region of the CD4 molecule. Mab chB4 could be used for the prevention, treatment, and functional cure of HIV infection.
Target
CD4
Target Alias Names
CD4 Molecule, T-Cell Surface Glycoprotein CD4, T-Cell Surface Antigen T4/Leu-3, CD4 Antigen (P55), CD4 Receptor, CD4 Antigen, CD4mut
Isotype/Mimetic
Chimeric (mouse/human) IgG1
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression