Description
10B3-H2L2 is the humanized version of murine antibody 10B3. H2L2 inhibit the myostatin-induced activation of cell signalling, resulting in luciferase expression in A204 cells.
Target
MSTN
Target Alias Names
Myostatin, GDF8, Growth Differentiation Factor 8, Growth/Differentiation Factor 8, MSLHP, GDF-8
Isotypes/Mimetics
Humanized IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression