Description
This is a monoclonal antibody which is engineered to be non-depleting via certain amino acid substitutions in the parent molecule, with amino acid substitution N297A in the heavy chain to increase serum half life.
Target
CD4
Target Alias Names
CD4 Molecule, T-Cell Surface Glycoprotein CD4, T-Cell Surface Antigen T4/Leu-3, CD4 Antigen (P55), CD4 Receptor, CD4 Antigen, CD4mut
Isotype/Mimetic
Human IgG1
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression