Description
This is a monoclonal antibody which is able to recognise and bind an epitope comprised in the TrkA amino acid sequence. Antibody CRB0089_IgG4 at the concentration of 20 μg/rat induced 100% reversion of hyperalgesia after 90 h of injection in the ipsilateral paw.
Target
NTRK1
Target Alias Names
Neurotrophic Receptor Tyrosine Kinase 1, Neurotrophic Tyrosine Kinase, Receptor, Type 1, High Affinity Nerve Growth Factor Receptor, TRK1-Transforming Tyrosine Kinase Protein, Tropomyosin-Related Kinase A, Tyrosine Kinase Receptor A, EC 2.7.10.1, P140-TrkA, Gp140trk, Trk-A
Isotype/Mimetic
Human IgG4
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression