Antibodies under a microscope

Ab04382-10.3

414H5

Description

Recombinant monoclonal antibody to CXCR4. Manufactured using AbAbТs Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 414H5. This is a reformatted human IgG1 Fc SilentЩ antibody, based on the original human IgG1 format, created for improved compatibility with existing reagents, assays and techniques.

Target

CXCR4

Target Alias Names

CD184, CXC-R4, CXCR-4, FB22, LAP-3, Fusin, HM89, LCR1, LESTR 1, NPYRL, C-X-C chemokine receptor type 4, Leukocyte-derived seven transmembrane domain receptor, Lipopolysaccharide-associated protein 3, LPS-associated protein 3, Stromal cell-derived factor 1 receptor, SDF-1 receptor

Isotype/Mimetic

IgG1

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Method

recombinantly reformatted hybridoma (from pre-2020 immunisation)

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression