Description
Recombinant monoclonal antibody to BACE2. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma 1/ 9 . This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG format, for improved compatibility with existing reagents, assays and techniques.
Target
BACE2
Target Alias Names
Beta-secretase 2, Aspartic-like protease, Aspartyl protease 1, Asp1, Beta-site amyloid precursor protein cleaving enzyme 2, Down syndrome aspartic protease, DRAP, Memapsin-1, Membrane-associated aspartic protease 1, theta-secretase
Isotype/Mimetic
IgG1
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression