Antibodies under a microscope

Ab00447-10.0

hu5c8 (Ruplizumab)

Description

Recombinant monoclonal antibody to CD40L. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma hu5c8 (Ruplizumab). NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar.

Target

CD40L

Target Alias Names

CD154, CD40 ligand, tumour necrosis factor ligand superfamily member 5, TNFSF5, tumour necrosis factor related activation protein, TRAP

Isotype/Mimetic

IgG1

Animal-Derived Biomaterials Used

No

Sequence Available

No

Original Discovery Methods

Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences

Original Discovery Information Provided On Datasheet

Yes

Antibody/Binder Origins

Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression