Description
Recombinant monoclonal antibody to EGFRvIII. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma L8A4. This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against human EGFRvIII (Fab) and one arm directed against mouse CD3e (scFv).
Target
EGFRvIII
Target Alias Name
Epidermal Growth Factor Receptor variant III
Isotype/Mimetic
IgG2a mCD3e KIH bispecific
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Method
recombinantly reformatted hybridoma (from pre-2020 immunisation)
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression