Description
Recombinant monoclonal antibody to CD20. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody 10F381 (rituximab). This reformatted human antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Target
CD20
Target Alias Names
Leu16, B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35 Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20
Isotype/Mimetic
IgM
Animal-Derived Biomaterials Used
No
Sequence Available
No
Original Discovery Methods
Naïve display libraries derived from human B cells, or naïve display libraries from animal B cells or Display libraries from synthetic or natural framework sequences
Original Discovery Information Provided On Datasheet
Yes
Antibody/Binder Origins
Animal-free discovery, Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression