Description
This product is a recombinant human antibody that recognizes ERBB3. The antibody inhibits NRG1 (e.g. NRG1-β1) from binding to ERBB3 and indirectly preventing ligand-induced dimerization of ERBB3. The antibody can be used in the desease research including Cancers.
Target
ERBB3
Target Alias Names
ERBB3, erb-b2 receptor tyrosine kinase 3, HER3, LCCS2, ErbB-3, c-erbB3, erbB3-S, MDA-BF-1
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression