Description
Anti-GPC3 antibody mouse-human chimeric antibody cGC33 with modified sugar chains has a high level of cytotoxic activity and therefore is useful as a cell growth inhibitor such as an anticancer agent.
Target
GPC3
Target Alias Names
Glypican 3, Intestinal Protein OCI-5, Glypican Proteoglycan 3, GTR2-2, MXR7, Heparan Sulphate Proteoglycan, Secreted Glypican-3, OCI-5, SGBS1, DGSX, SGBS, SDYS, OCI5, SGB
Isotypes/Mimetics
Chimeric (mouse/human) IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression