Description
4H5 is an antibody which is humanized from murine antibody EA2. 4H5 exhibits approximately a 20 fold increase of affinity when compared with chimeric Fab EA2.
Target
EPHA2
Target Alias Names
EPH Receptor A2, Tyrosine-Protein Kinase Receptor ECK, EC 2.7.10.1, ECK, Epithelial Cell Receptor Protein Tyrosine Kinase, Soluble EPHA2 Variant 1, Epithelial Cell Kinase, EC 2.7.10, CTRCT6, ARCC2, CTPP1, EphA2, CTPA
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression