Description
Provided are antibodies that specifically bind TFPI and inhibit an activity thereof. Such antibodies are useful for treating bleeding disorders and shortening clotting time.
Target
TFPI
Target Alias Names
TFPI, tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor), EPI, TFI, LACI, TFPI1, tissue factor pathway inhibitor, anti-convertin, extrinsic pathway inhibitor
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression