Description
This product is a recombinant antibody that recognizes Human BDNF. The monoclonal antibody R3BH1 reacts with the epitope (C-terminus) of BDNF. Anti-BDNF antibody R3BH1 and TrkB-Fc molecule inhibits TrkB receptor activation and downstream signalling mediated by BDNF, as measured by phosphorylated pERK activity.
Target
BDNF
Target Alias Names
Brain Derived Neurotrophic Factor, Neurotrophin, Abrineurin, Brain-Derived Neurotrophic Factor, ANON2, BULN2
Isotypes/Mimetics
Chimeric (chicken/human) lgG1, λ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression