Description
This product is a recombinant human antibody that recognizes MST1R. The IMC-41A10 was selected from a phage display library. The ability of the anti-RON antibody IMC-41A10 to bind to recombinant human RON receptor and to block the MSP/RON interaction was measured using ELISA. The antibody can bind to the beta extracellular domain of RON and block the MSP/RON interaction.
Target
MST1R
Target Alias Names
Macrophage Stimulating 1 Receptor, PTK8 Protein Tyrosine Kinase 8, C-Met-Related Tyrosine Kinase, MSP Receptor, EC 2.7.10.1, P185-Ron, CDw136, PTK8
Isotypes/Mimetics
Human IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression