Description
This product is a recombinant human antibody that recognizes IL17A. Antibody h142 bound specifically to human IL-17A, with no binding detected to the closely related cytokines IL-17C and IL-17F. It functionally blocked IL-17A binding to IL-17RA, neutralized IL-17A-dependent signaling and had a binding affinity of 80 nM.
Target
IL17A
Target Alias Name
Interleukin 17A
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression