Description
An agonist anti-trkC antibody can be used in the treatment and prevention of neuropathies, such as sensory neuropathies, including taxol-induced sensory neuropathy, cisplatin-induced sensory neuropathy, and pyridoxine-induced sensory neuropathy.
Target
NTRK3
Target Alias Names
TRKC, GP145-TrkC, gp145(trkC)
Isotypes/Mimetics
Human IgG2a, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression