Description
Provided is a recombinant human antibody that recognizes HAVCR1. It binds to TIM-1 antigen expressed on ACHN and CAKI-2 cells as determined by FACS, and can induce CAKI-1 cell death. The antibody was purified by affinity chromatography.
Target
HAVCR1
Target Alias Names
Hepatitis A Virus Cellular Receptor 1, Kidney Injury Molecule 1, T-Cell Immunoglobulin Mucin Family Member 1, T-Cell Immunoglobulin Mucin Receptor 1, T-Cell Membrane Protein 1, HAVCR-1, TIMD-1, KIM-1, TIM-1
Isotypes/Mimetics
Human IgG4, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression