Description
Antibody 4F2 is a humanized monoclonal antibody that binds to a human EphB4 antigen, may inhibit tumor growth and mediate ADCC, CDC, and apoptosis for the treatment of human malignancies and vasculogenesis-related disorders and diseases.
Target
EPHB4
Target Alias Names
EPH Receptor B4, Tyrosine-Protein Kinase TYRO11, Hepatoma Transmembrane Kinase, EC 2.7.10.1, TYRO11, MYK1, HTK, Tyrosine-Protein Kinase Receptor HTK, Soluble EPHB4 Variant 1, Soluble EPHB4 Variant 2, Soluble EPHB4 Variant 3, Ephrin Receptor EphB4, EC 2.7.10, EphB4
Isotypes/Mimetics
Humanized IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression