Description
This antibody specifically binds to PD-L1. The antibody was generated by selection of phage clones with a high affinity. This monoclonal antibody could block the binding of hPDL1 to hPD, promote the T-cell production of cytokines including IFNγ and inhibit PD-L1-mediated immunosuppression. The product was expressed in mammalian cells with chemically defined culture media and was purified by affinity chromatography. This product could be used in the research of immunotherapy of neoplastic and infectious diseases.
Target
CD274
Target Alias Names
B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1, programmed cell death 1 ligand 1, B7 homolog 1, CD274 antigen, PDCD1 ligand 1
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression