Description
This product is a recombinant human antibody that recognizes CD70 with a KD of approximately 5.1 nM for CD70-transfected CHO cells. anti-CD70 antibody is internalized into renal carcinoma cancer cell lines. When conjugated to the toxin, anti-CD70 antibody is cytotoxic to kidney cancer cells.
Target
CD70
Target Alias Names
CD27L, CD27-L, CD27LG, TNFSF7, TNLG8A
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression