Description
The anti-DDR1 antibody APE05571 exhibits high affinity for DDR1 and antagonizes DDR1 signaling, demonstrating that this antibody is a functional DDR1 antagonist.
Target
DDR1
Target Alias Names
Discoidin Domain Receptor Tyrosine Kinase 1, CD167 Antigen-Like Family Member A, Protein-Tyrosine Kinase RTK-6, Mammary Carcinoma Kinase 10, Tyrosine-Protein Kinase CAK, Cell Adhesion Kinase, Tyrosine Kinase DDR, EC 2.7.10.1, EDDR1, NTRK4, PTK3A, HGK2, RTK6, TRKE, CAK, NEP, Neurotrophic Tyrosine Kinase, Receptor, Type 4, Discoidin Domain Receptor Family, Member 1, Epithelial Discoidin Domain Receptor 1, Discoidin Receptor Tyrosine Kinase, PTK3A Protein Tyrosine Kinase 3A, Neuroepithelial Tyrosine Kinase, Protein-Tyrosine Kinase 3A, CD167a Antigen, EC 2.7.10, MCK-10, CD167, MCK10, TRK E, PTK3, DDR
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression