Description
Human antibody against MST1R. MOR07924 clearly suppressed MSP-promoted proliferation of T-47D cells. Viability of PC3 cells was greatly reduced by the treatment with MOR07924, suggesting the potential of this antibody to internalize.
Target
MST1R
Target Alias Names
MST1R, macrophage stimulating 1 receptor (c-met-related tyrosine kinase), RON, PTK8, CD136, CDw136, macrophage-stimulating protein receptor, p185-Ron, MSP receptor, RON variant 21, RON variant E2E3, MST1R variant RON30, MST1R variant RON62, soluble RON variant 1, soluble RON variant 2, soluble RON variant 3, soluble RON variant 4, c-met-related tyrosine kinase, PTK8 protein tyrosine kinase 8
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression