Description
This antibody specifically binds human and Macaca fascicularis lysosomal-associated membrane protein 1 (LAMP1). LAMP1, also known as CD107 antigen-like family member A (CD107a), is highly expressed in late endosomes and lysosomes. This antibody is a chimeric (mouse/human) monoclonal antibody that could induce an anti-tumor activity in vivo in a murine model.
Target
LAMP1
Target Alias Names
LAMPA, CD107a, LGP120
Isotype/Mimetic
Chimeric (mouse/human) IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression