Description
The antibody specifically bind human RSPO3 proteins and modulate β-catenin activity. The antibody inhibits β-catenin signaling.
Target
RSPO3
Target Alias Names
RSPO3, R-spondin 3, PWTSR, THSD2, CRISTIN1, R-spondin-3, R-spondin 3 homolog, roof plate-specific spondin-3, protein with TSP type-1 repeat, thrombospondin, type I, domain containing 2, thrombospondin type-1 domain-containing protein 2
Isotypes/Mimetics
Humanized IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression