Description
Recombinant monoclonal antibody to SIRPαV1 and V2. Clone 29-AM4-5 is a humanized antibody that can be potentially used in the treatment of Acute myeloid leukemia (AML).
Target
SIRPA
Target Alias Names
SIRPA, signal-regulatory protein alpha, BIT, MFR, P84, SIRP, MYD-1, SHPS1, CD172A, PTPNS1, tyrosine-protein phosphatase non-receptor type substrate 1, myd-1 antigen, inhibitory receptor SHPS-1, macrophage fusion receptor, CD172 antigen-like family member A, tyrosine phosphatase SHP substrate 1, brain-immunoglobulin-like molecule with tyrosine-based activation motifs
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression