Description
This product is a recombinant humanized antibody that recognizes human 4-1BB. Mab Hz4B4-2 has a high affinity for human 4-1BB and exhibits sequence similarity to human antibody. It can be used to treat graft rejections, autoimmune disease such as RA and act as an immunosuppressant in humans without much side-effect.
Target
TNFRSF9
Target Alias Names
TNF Receptor Superfamily Member 9, T-Cell Antigen 4-1BB Homolog, 4-1BB Ligand Receptor, CD137 Antigen, CDw137, CD137, ILA, Interleukin-Activated Receptor, Homolog Of Mouse Ly63, Tumor Necrosis Factor Receptor Superfamily, Member 9, Hz4B4-2, MAb Hz4B4-2
Isotype/Mimetic
Humanized IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression