Description
Recombinant monoclonal antibody specially binds to human the immunoglobulin–like ectodomains (residues1-185) of glycoprotein VI, also called D1D2. 10B12 is a human monoclonal antibody that can be useful in the treatment of damage to blood vessels.
Target
GP6
Target Alias Names
Glycoprotein VI Platelet, Glycoprotein VI (Platelet), Glycoprotein 6, GPVI, Platelet Collagen Recept, Platelet Glycoprotein VI, BDPLT11, GPIV
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression