Description
This is a human pemphigus vulgaris monoclonal autoantibodies isolated by phage display. The clone (D31)12a/5 is a nonpathogenic antibody recognizes both Dsg1 and Dsg3, wherewa it demonstrates only 5–26% inhibition of binding to Dsg3 by EDTA.
Target
DSG1
Target Alias Names
Desmoglein 1, Pemphigus Foliaceus Antigen, Desmosomal Glycoprotein 1, Cadherin Family Member 4, CDHF4, DG1, EPKHIA, EPKHE, PPKS1, SPPK1, DSG, DGI
Isotype/Mimetic
Human IgG
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression