Description
Antibody clone h60.3 is specific to CD18. Clone 60.3 binds to the CD18 component of the beta 2 integrin family of adhesion molecules. The mAb has potential clinical application in blocking the neutrophil-mediated organ damage which occurs following a myocardial infarct or hemorrhagic shock.
Target
ITGB2
Target Alias Names
LAD, CD18, MF17, MFI7, LCAMB, LFA-1, MAC-1
Isotypes/Mimetics
Humanized IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression