Description
Provided is a chimeric antibody specific for human ganglioside (GD3), designated KM871. The chimeric KM871 was more effective in killing GD3-expressing tumor cells than was the mouse counterpart KM641.
Target
GD3
Target Alias Names
Ganglioside, GD3
Isotypes/Mimetics
Chimeric (mouse/human) IgG1, κ
Animal-Derived Biomaterials Used
None
Sequence Available
No
Original Discovery Method
Human-derived phage display
Original Discovery Information Provided On Datasheet
No
Antibody/Binder Origins
Animal-free discovery, In vitro recombinant expression