Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Target
HDAC4
Target Alias Names
Histone deacetylase 4, HD4, HDAC4, AHO3, BDMR
Isotype/Mimetic
Rabbit IgG
Animal-Derived Biomaterials Used
None
Sequence Available
Yes
Original Discovery Method
Unknown
Antibody/Binder Origins
Unknown discovery source/method, In vitro recombinant expression