Description
Tri-Methyl-Histone H3 (Lys79) (E8B3M) Rabbit mAb recognizes endogenous levels of histone H3 protein when tri-methylated at Lys79. This antibody shows some cross-reactivity to histone H3 that is di-methylated on Lys79, but does not cross-react with non-methylated or mono-methylated histone H3 Lys79. The antibody does not cross-react with histone H3 methylated at Lys4, Lys9, Lys27, or Lys36, and does not cross-react with any other methylated histone proteins. Monoclonal antibody is produced by immunizing animals with a synthetic peptide containing histone H3 tri-methyl lysine 79.
Target
H3 (Lys79) trimethylate
Target Alias Names
H3C1, H3
Isotype/Mimetic
IgG
Animal-Derived Biomaterials Used
BSA
Sequence Available
Yes
Original Discovery Method
Immunization
Antibody/Binder Origins
Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation