Antibodies under a microscope

38938

Phospho-PKC (pan) (gamma Thr514) (D6Y3D) Rabbit mAb

Description

Phospho-PKC (pan) (gamma Thr514) (D6Y3D) Rabbit mAb detects endogenous levels of PKC alpha, beta I, beta II, gamma, delta, epsilon, eta, and theta isoforms only when phosphorylated at a residue homologous to Thr514 of human PKC gamma. This antibody does not detect PKC phosphorylated at other sites. Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr514 of human PKC gamma.

Targets

PKCbeta1 (Thr500) phosphate, PKCalpha (Thr497) phosphate, PKCeta (Thr513) phosphate, PKCdelta (Thr507) phosphate, PKCbeta2 (Thr500) phosphate, PKCtheta (Thr538) phosphate, PKCepsilon (Thr566) phosphate, PKCgamma (Thr514) phosphate

Target Alias Names

PRKCB, PRKCA, PRKCH, PRKCD, PRKCB, PRKCQ, PRKCE, PRKCG, PKCB, PKCA, PKCH, PKCD, PKCB, PKCT, PKCE, PKCG

Isotype/Mimetic

IgG

Animal-Derived Biomaterials Used

BSA

Sequence Available

Yes

Original Discovery Method

Immunization

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation