Antibodies under a microscope

2758

ISG15 (22D2) Rabbit mAb

Description

ISG15 (22D2) Rabbit mAb detects endogenous levels of the uncleaved precursor form of ISG15 protein. This antibody does not recognize the activated (cleaved) or conjugated forms of ISG15. The antibody does not cross-react with other ubiquitin family members, including ubiquitin, SUMO-1, SUMO-2, SUMO-3 and NEDD8. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to amino acids at the carboxy terminus of human ISG15 protein.

Target

ISG15

Target Alias Name

ISG15

Isotype/Mimetic

IgG

Animal-Derived Biomaterials Used

BSA

Sequence Available

Yes

Original Discovery Method

Immunization

Antibody/Binder Origins

Animal-dependent discovery (in vitro display, OR immunisation pre-2020), In vitro recombinant expression, Animal-derived biomaterials used in production or final formulation