FairJourney Biologics

Always trying to implement novel techniques and technologies to provide high-quality antibodies efficiently and cost-effectively, the methods include:
– Antibody Discovery and Engineering: Use of Mammalian Display and Phage Display technologies, utilizing a diverse repertoire of libraries. These include the Explorer Semi-synthetic Library, Non-immune Libraries (human Fab and ScFv and llama VHH), and Immune Libraries (immunization capabilities on five different species: rabbit, rat, mouse, llama and chicken), allowing to generate a wide variety of high-quality and optimized antibodies.
– Recombinant Production Methods: Transient production of antibodies (range of standard formats to complext molecules) and antigens in CHO and HEK cells, ranging from highthroughput (96 and 24-well plates) to several liter capacity (up to 100L capacity). Stable production in CHOZN cell lines (average yields from 4-8g/L). This flexibility enables to optimize the production process according to the specific requirements of each project.
– Cell line engineering: Transient and stable cell line transfection for target expression, reporter cell line generation, functional cells, and others.
– Functional Assays and Biophysical Characterization: Use of several advanced techniques to assess the functionality and biophysical properties of the antibodies. These capabilities include but are not limited to SPR, cell-based assays, stability assessments, early and late developability. This ensures that the antibodies are not only high in quality but also effective in their intended applications.

FairJourney Biologics’ processes can be animal-free from the early discovery phases throughout the stable cell line development of the antibodies.